Glossary of Background Screening Terms
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This glossary should not be considered to be all-inclusive or intended to constitute legal advice. It is important to consult legal counsel when making employment decisions.
Drug Testing Terms
Accession Number
A number assigned to each specimen by the laboratory. This number stays with the specimen it's entire lifetime. It is used to identify and track a specimen every step from the time it arrives at the laboratory until the result is reported.
Adulterated Specimen
A specimen that contains a substance that is not expected to be present in human urine, or contains an expected substance at a concentration so high that it is not consistent with human urine.
Affidavit
A form that must be signed by the collector to correct a problem on the original Chain of Custody form. For example, if the date was missing, incorrect, or the collector's signature was missing.
Air Blank
In evidential breath testing devices (EBTs) using gas chromatography technology, a reading of the device's internal standard. In all other EBTs, a reading of ambient air containing no alcohol.
Alcohol
The intoxicating agent in beverage alcohol, ethyl alcohol or other low molecular weight alcohols, including methyl or isopropyl alcohol.
Alcohol Concentration
The alcohol in a volume of breath expressed in terms of grams of alcohol per 210 liters of breath as indicated by a breath test under this part.
Alcohol Concentration Test
A subsequent test using an EBT, following a screening test with a result of 0.02 or greater, that provides quantitative data about the alcohol concentration.
Alcohol Screening Device
A breath or saliva device, other than an EBT, that is approved by the National Highway Traffic Safety Administration (NHTSA) and placed on a conforming products list (CPL) for such devices.
Alcohol Screening Test
An analytic procedure to determine whether an employee may have a prohibited concentration of alcohol in a breath or saliva specimen.
Alcohol Testing Site
A place selected by the employer where employees present themselves for the purpose of providing breath or saliva for an alcohol test.
Alcohol Use
The drinking or swallowing of any beverage, liquid mixture or preparation (including any medication), containing alcohol.
Blind Specimen
A specimen submitted to a laboratory for quality control testing purposes, with a fictitious identifier, so that the laboratory cannot distinguish it from an employee specimen. Also known as “blind performance test specimen”.
Breath Alcohol Technician
A person who instructs and assists employees in the alcohol testing process and operates an evidential breath testing device.
Canceled Test
A drug test that is canceled due to a problem with the testing process itself. Canceled tests do not yield positive or negative results.
Chain of Custody
The procedure used to document the handling of the urine specimen from the time the employee gives the specimen to the collector until the specimen is destroyed. This procedure uses the Federal Drug Testing Custody and Control Form (CCF).
Clinic
A medical facility that can be used as a collection site.
Collection Site
A place selected by the employer where employees present themselves for the purpose of providing a urine specimen for a drug test.
Collector
A person who instructs and assists employees at a collection site, who receives and makes an initial inspection of the specimen provided by those employees, and who initiates and completes the Federal Drug Testing Custody and Control Form (CCF).
Confirmation Drug Test
A second, definitive analytical procedure performed on a urine specimen to identify and quantify the presence of a specific drug or drug metabolite following a non-negative initial screening result. Confirmation testing is typically performed using gas or liquid chromatography with mass spectrometry (GS/MS or LC/MS).
Confirmation Validity Test
A secondary laboratory test performed on a urine specimen to verify and support an initial specimen validity test result, such as adulteration, substitution, or dilution. This testing further evaluates specimen integrity rather than the presence of drugs or drug metabolites.
Confirmation Drug Test Result
The verified result of a laboratory confirmation drug test that is reported to and reviewed by a Medical Review Officer (MRO) prior to final determination.
Consortium/Third-Party Administrator (C/TPA)
A service agent that provides or coordinates drug and alcohol testing services on behalf of employers. A consortium/third‑party administrator typically performs administrative and program management functions related to the operation of an employer’s drug and alcohol testing program, such as coordinating testing services, maintaining records, and supporting compliance requirements.
Continuing Education
Training for medical review officers (MROs) and substance abuse professionals (SAPs) who have completed qualification training and are performing MRO or SAP functions, designed to keep MROs and SAPs current on changes and developments in the DOT drug and alcohol testing program
Designated Employer Representative
An employee authorized by the employer to take immediate action(s) to remove employees from safety-sensitive duties, or cause employees to be removed from these covered duties, and to make required decisions in the testing and evaluation processes.
Dilute Specimen
A specimen with creatinine and specific gravity values lower than expected for human urine.
DOT (Department of Transportation)
encompass all DOT agencies, including, but not limited to, the United States Coast Guard (USCG), the Federal Aviation Administration (FAA), the Federal Railroad Administration (FRA), the Federal Motor Carrier Safety Administration (FMCSA), the Federal Transit Administration (FTA), the National Highway Traffic Safety Administration (NHTSA), the Pipeline and Hazardous Materials Safety Administration (PHMSA), and the Office of the Secretary (OST).
DOT Drug Test
A drug test conducted in accordance with Department of Transportation (DOT) regulations on an individual who is subject to DOT drug testing requirements. DOT drug tests are performed under the authority of applicable DOT agencies and follow the procedures outlined in 49 CFR Part 40.
Drug Metabolites
Chemical substances produced when the body processes a drug. Drug metabolites are typically what laboratories test for in a drug screen, as their presence indicates prior use of a specific substance. Different drugs produce specific metabolites that are used to identify the drug consumed.
Drugs
Substances for which testing may be conducted under workplace drug testing programs. In DOT‑regulated testing, required substances include marijuana (cannabinoids), cocaine, amphetamines, opiates, and phencyclidine (PCP), as defined by DOT regulations. In non‑DOT testing programs, the drugs tested may vary based on employer policy, state law, or testing objectives and may include additional substances beyond the DOT‑mandated panel.
Employee/Donor/Applicant
Any individual who is subject to drug and/or alcohol testing under a workplace testing program. This may include current employees, applicants for employment, or other individuals required to undergo testing based on employer policy, regulatory requirements, or the circumstances of the test. In DOT‑regulated programs, this includes individuals performing safety‑sensitive functions and applicants subject to pre‑employment testing under DOT regulations.
Employee Assistance Program (EAP)
Third-party organizations contracted with employers that provide educational and counseling services. Types of services and who may be eligible vary and will be detailed in employee benefit packages.
Employer
A person or entity that employs one or more individuals and establishes or administers a workplace drug and/or alcohol testing program. This includes employers’ officers, representatives, and management personnel responsible for program oversight. In DOT‑regulated programs, an employer is any person or entity subject to DOT agency regulations requiring compliance with applicable drug and alcohol testing requirements.
Error Correction Training
Training provided to breath alcohol technicians (BATs), collectors, and screening test technicians (STTs) following an error that resulted in the cancellation of a drug or alcohol test.
Evidential Breath Testing Device (EBT Device)
A device approved by NHTSA for the evidential testing of breath at the .02 and .04 alcohol concentrations, placed on NHTSA's Conforming Products List (CPL) for Evidential Breath Measurement Devices and identified on the CPL as conforming with the model specifications available from NHTSA's Traffic Safety Program
HHS (Health and Human Services)
The Department of Health and Human Services or any designee of the Secretary, Department of Health and Human Services.
Impairment Standard
Often referred to as a “per se” limit, a legal or regulatory threshold that defines impairment based on a measured concentration of a substance. Under an impairment standard, an individual may be considered impaired when their test result exceeds the established cutoff level, even if there is no direct evidence of observable impairment or adverse effects.
Impairment
The deterioration of an individual’s judgment and/or physical ability impacts their ability to function productively and/or safely. Drug or alcohol use, sleep deprivation, or distraction could all be impairing.
Initial Drug Test
The first analytical test performed on a specimen to determine whether the presence of drugs or drug metabolites is below established cutoff levels or if further (confirmation) testing is required. This test is used to differentiate a negative result from a non‑negative result.
Initial Validity Test
The first laboratory test performed on a specimen to assess specimen integrity and determine whether it is consistent with normal human urine, including evaluation for adulteration, dilution, or substitution.
Invalid Drug Test
The result of a drug test for a urine specimen that contains an unidentified adulterant or an unidentified interfering substance, has abnormal physical characteristics, or has an endogenous substance at an abnormal concentration that prevents the laboratory from completing or obtaining a valid drug test result.
Medical Review Officer (MRO)
A licensed physician who is responsible for receiving and reviewing laboratory drug test results and evaluating potential medical explanations for non-negative findings. The MRO determines the final result of a drug test before it is reported to the employer and serves as an independent, confidential safeguard in the drug testing process.
Negative Result (Drug Testing)
A final test result indicating that the concentration of drugs or drug metabolites in a specimen is below the applicable cutoff levels, and no further testing or review is required.
Non-negative (Drug Testing)
An initial, preliminary screening result that indicates a specimen is not clearly negative, suggesting the presence of drugs, metabolites, or issues like adulteration, substitution, or dilution. Non-negative results are not final and require additional laboratory confirmation testing (e.g., GC-MS) and/or Medical Review Offer (MRO) review before a final determination is made.
Office of Drug and Alcohol Policy and Compliance (ODAPC)
DOT division that oversees drug and alcohol testing for transportation workers in aviation, trucking, rail, and transit industries.
Positive Result (Drug Testing)
A final test result indicating that the concentration of a drug or drug metabolite in a specimen meets or exceeds the applicable cutoff level and has been confirmed through required laboratory testing and Medical Review Officer (MRO) review.
Primary Specimen (Drug Testing)
The portion of a collected specimen that is opened and tested by the initial laboratory to determine the presence of drugs or drug metabolites and to perform specimen validity testing. Results from the primary specimen are used for initial screening, confirmation testing, and Medical Review Officer (MRO) review.
Recent Use
For cannabis testing purposes, this refers to tests designed to detect proximate use that occurred within hours prior to specimen collection.
Safety Sensitive Position
a job role where an employee’s impaired performance, due to alcohol or drug use, could result in a significant incident affecting the health and safety of the employee, coworkers, the public, or cause substantial property damage.
These positions often involve operating heavy machinery, driving commercial vehicles, handling hazardous materials, or managing public safety.
Screening Test Technician (STT)
An individual who is trained and qualified to conduct alcohol screening tests, including instructing and assisting individuals during the testing process and operating approved alcohol screening devices. An STT performs screening tests only and does not conduct alcohol confirmation tests using an evidential breath testing device (EBT).
Service Agent
Any person or entity, other than an employee of the employer, who provides or coordinates services related to workplace drug and/or alcohol testing programs. In DOT-regulated programs, service agents include organizations or individuals who perform functions specified under DOT regulations in support of employer compliance.
Specimen Bottle
A bottle that, once filled, sealed, and labeled according to applicable collection procedures, is used to hold and protect a urine specimen during storage and transportation to the laboratory.
Specimen ID
A unique identifier assigned to a specimen at the collection site at the time of collection. This identifier appears on the Chain of Custody Form and specimen bottle and stays with the specimen through its entire life. It is used to maintain chain of custody and identify or track the specimen from the moment of collection until the result is reported.
Split Specimen
A portion of a urine specimen that is sealed and retained unopened after collection and initially sent with the primary specimen to the first laboratory. The split specimen is preserved for testing at a second laboratory if the donor requests reanalysis following a verified positive, adulterated, or substituted result on the primary specimen.
Stand-Down
The practice of temporarily removing an employee from the performance of safety-sensitive functions based solely on a laboratory report to the Medical Review Officer (MRO) indicating a confirmed positive, adulterated, or substituted drug test, before the MRO has completed verification of the test result.
Substance Abuse Professional
A person who evaluates employees who have violated DOT drug and alcohol regulations and makes recommendations concerning education, treatment, follow-up testing, and aftercare.
Substituted Specimen
Specimen with creatinine and specific gravity values that are so diminished that they are not consistent with human urine.
Temperature Strip
A strip affixed to or used with a urine specimen bottle to determine whether the specimen’s temperature is within the expected range of 90-100 degrees Fahrenheit (32-38 degrees Celsius) at the time of collection. This helps to ensure that tampering has not occurred.
Verified Test
A drug test result or specimen validity test result from an HHS-certified laboratory that has undergone review by a Medical Review Officer (MRO) and finalized as the official test result.
